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Testing Status of Perfluorohexane sulfonate potassium salt (PFHSKslt) M060100

CASRN: 3871-99-6

Formula: C6-H-F13-O3-S.K

Synonyms/Common Names

  • Perfluorohexane-1-sulphonic acid - potassium salt
  • Potassium perfluorohexane-1-sulphonate
  • 1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexane-1-su1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonic

Short-Term Toxicity

  • 28 days (Gavage)  (C06100)  Completed 
    • TOX-96 
      Toxicity Studies of Perfluoroalkyl Sulfonates (Perfluorobutane Sulfonic Acid, Perfluorohexane Sulfonate Potassium Salt, and Perfluorooctane Sulfonic Acid) Administered by Gavage to Sprague Dawley (Hsd:Sprague Dawley SD) Rats (Revised)
    • Rats: Harlan Sprague-Dawley
    • Dose: M: 0, 0.625, 1.25, 2.5, 5, or 10 mg/kg; F: 0, 3.12, 6.25, 12.5, 25, or 50 mg/kg.

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K10127)  Completed 
    • Citation: Huang MC, Dzierlenga AL, Robinson VG, Waidyanatha S, DeVito MJ, Eifrid MA, Granville CA, Gibbs ST, Blystone CR. Toxicokinetics of perfluorobutane sulfonate (PFBS), perfluorohexane-1-sulphonic acid (PFHxS), and perfluorooctane sulfonic acid (PFOS) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration. Toxicol Rep. 2019 Jun 28;6:645-655. doi: https://doi.org/10.1016/j.toxrep.2019.06.016. Erratum in: Toxicol Rep. 2020 Dec 22;8:28-29. Erratum in: Toxicol Rep. 2021 Feb 18;8:365.Pubmed Abstract
    • Male and Female Rats [R]: Fischer 344
    • Dose: (gavage) 4, 16, 32 mg/kg [R]. (intravenous) 4 mg/kg [R].

Genetic Toxicology

  • Micronucleus  (G06100)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative