Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate M20247

 

CASRN: 6197-30-4

Formula: C24-H27-N-O2

Synonyms/Common Names

  • Octocrylene
  • 2-Propenoic acid, 2-cyano-3,3-diphenyl-, 2-ethylhexyl ester (9CI)

Special Studies

  • 3 days Hershberger Assay (Gavage)  (K20247B)  Completed 
    • Male Rats: Harlan Sprague-Dawley
    • Dose: 20, 64, or 200 mg/ml.
  • 3 days Uterotrophic Assay (Gavage)  (K20247)  Completed 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 5 mL/kg.

Genetic Toxicology

  • Salmonella  (066654)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 

in vitro Testing

  • H295R Steroidogenesis Assay  (V20247)  Completed 
    • H295R Steroidogenesis Assay
    • Human (Cell Lines)
  • Androgen Receptor Binding Assay  (V20247B)  Completed 
    • Androgen Receptor Binding Assay
    • Rats: Sprague Dawley
  • Estrogen Receptor Binding Assay  (V20247C)  Completed 
    • Estrogen Receptor Binding Assay
    • Rats: Sprague Dawley
  • Androgen Receptor Transactivation Assay  (V20247D)  Completed 
    • Androgen Receptor Transactivation Assay
    • Human (Cell Lines)
  • Estrogen Receptor Transactivation Assay  (V20247E)  Completed 
    • Estrogen Receptor Transactivation Assay
    • Human (Cell Lines)
  • Human Recombinant Aromatase Assay  (V20247G)  Completed 
    • Human Recombinant Aromatase Assay
    • Human (Cell Lines)