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2',3'-Dideoxyinosine (69655-05-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6022927

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Dideoxyinosine (69655-05-6).
Micronucleus - Mice
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  • Male: Negative
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  • Male: Negative
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  • Male: Negative
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  • Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Dideoxyinosine (69655-05-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Dideoxyinosine (69655-05-6).
Bacterial Mutagenicity
View
  • Weakly Positive

Citation Information

NTP. 2',3'-Dideoxyinosine (69655-05-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Witt KL, Tice RR, Wolfe GW, Bishop JB. Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment. Environ Mol Mutagen. 2004;44(4):321-8.
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2',3'-Dideoxyinosine (AIDS Initiative) (69655-05-6) in Micronucleus Study 865388 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyinosine (AIDS Initiative) (69655-05-6) in Micronucleus Study A08622 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyinosine (AIDS Initiative) (69655-05-6) in Micronucleus Study A20001 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyinosine (AIDS Initiative) (69655-05-6) in Micronucleus Study A90144 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyinosine (AIDS Initiative) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 783382
Summary Data

Other NTP Studies

180-Day Immunotoxicity Evaluation (IMM94006) of 2',3'-Dideoxyinosine (Aids Initiative) (69655-05-6) in B6C3F1 Mice via Gavage
B6CF1 Mice Individual and Summary Data
Toxicokinetic Evaluation (K88074) of 2',3'-Dideoxyinosine (DDI) (DTXSID6022927) in Mouse
Data

NTP Data Collections