Testing Status of Oleic acid diethanolamine condensate M910075

CASRN: 93-83-4

Related: 13961-86-9 (OLEIC ACID DIETHANOLAMINE)

Formula: C22-H43-N-O3

Synonyms/Common Names

• N,N-di(2-Hydroxyethyl)oleamide
• 9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (Z)- (9CI)
• Oleamide DEA
• Oleic acid diethanolamide

Short-Term Toxicity

• 13 weeks (Topical Application)  (C91014)  Completed 
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R: 0, 25, 50, 100, 200, OR 400 MG/KG; 20/SEX/GROUP M: 0, 50, 100, 200, 400, OR 800 MG/KG; 10/SEX/GROUP.

Long-Term Carcinogenicity

• 2 years (Topical Application)  (C91014)  Completed 
  • TR-481 (NIH Number: 99-3971)  (Peer Review Approval 12/10/1997A )
    Toxicology and Carcinogenesis Studies of Oleic Acid Diethanolamine Condensate in F344/N Rats and B6C3F1 Mice (Dermal Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
    • Male Rats No Evidence 
    • Female Rats No Evidence 
    • Male Mice No Evidence 
    • Female Mice No Evidence 
  • Dose: R: 0, 50, OR 100 MG/KG; 50/SEX/GROUP M: 0, 15, OR 30 MG/KG; 55/SEX/GROUP.

Genetic Toxicology

• Micronucleus  (A72594)  Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Mouse Lymphoma  (932123)  Completed 
  • Mice
  •  Negative 
• Salmonella  (669959)  Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Negative 

Organ Systems Toxicity

• Immunotoxicity (Topical Application)  (IMM90004)  Completed 
  • Female Mice: B6C3F1
  • Mice Female Negative 
  • Dose: 0, 1, 3, 10%.