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Testing Status of Carbonyl sulfide M950074

CASRN: 463-58-1

Formula: C-O-S

Synonyms/Common Names

  • Carbon monoxide monosulfide
  • Carbon oxide sulfide
  • Oxycarbon sulfide

Special Studies

  • Toxicokinetic Study (Gavage; Inhalation; Gavage; Inhalation)  (S0655)  Completed 
    • Male Rats [R]: F344/N; Male Mice [M]: B6C3F1
    • Dose: (gavage) 50 mg/kg [R,M]. (inhalation) 250, 500 ppm @ 4 hours [R]. (inhalation) 250 to 500 ppm @ 4 hours [M].

Genetic Toxicology

  • Salmonella  (A35125)  Completed 
    •  Weakly Positive 

Organ Systems Toxicity

  • 2 weeks Neurotoxicology Assessment (Inhalation)  (NTA20001)  Completed 
    • Male and Female Rats: F344/N
    • Dose: 0, 300, 400, OR 500 PPM.
  • 12 weeks Neurotoxicology Assessment (Inhalation)  (NTA20002)  Completed 
    • Male and Female Rats: F344/N
    • Dose: 0, 200, 300, OR 400 PPM.