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Testing Status of Toxic equivalency factor evaluation (PCB Mixture; PCB 126/PCB 118) M970041


Synonyms/Common Names

  • PCB Mixture (Toxic equivalency factor evaluation)
  • Toxic equivalency factor evaluation (PCB Mixture (PCB 126/PCB 118))


  • 31508-00-6 - 2,3',4,4',5-Pentachlorobiphenyl
  • 57465-28-8 - 3,3,4,4,5-Pentachlorobiphenyl (PCB 126)
  • 31508-00-6 - Toxic equivalency factor evaluation (PCB 118)
  • 57465-28-8 - TEF transgenics (PCB 126)
  • 57465-28-8 - Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl)

Long-Term Carcinogenicity

  • 2 years (Gavage)  (C96022)  Completed 
    • TR-531 (NIH Number: 07-4467)  (Peer Review Approval 12/09/2004A )
      Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
    • Rats: Harlan Sprague-Dawley
    • Dose: Female rats only (PCB 118/PCB 126): 0, 7, 22, 72, 216, or 360 ng/kg; 50/dose.
    • Carcinogenesis Results
      • Female Rats Clear Evidence