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Testing Status of Transgenic model evaluation (Ethinyl estradiol) M970046

CASRN: 57-63-6

Formula: C20-H24-O2

Synonyms/Common Names

  • Ethinyl estradiol (Transgenic model evaluation)
  • 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha) (9CI)

Short-Term Toxicity

  • 2 weeks (Topical Application)  (C97011E)  Completed 
    • Mice: FVB/N
    • Dose: 0, 30, 60, 120, 180, OR 360 UG/KG; 5/SEX/DOSE; 2X/WEEK.
  • 2 weeks (Gavage)  (C97011F)  Completed 
    • Mice: FVB/N
    • Dose: 0, 30, 60, 120, 180, OR 360; 5/SEX/DOSE; 2X/WEEK.
  • 26 weeks (Topical Application)  (C97011E)  Completed 
    • Mice: FVB/N; Mice: Tg.AC (FVB/N) Homozygous
    • Dose: TG.AC MICE AT 0, 33, 265, OR 530 UG/KG AND FVB MICE AT 0 OR 530 UG/KG; 15/SEX/DOSE; 2X/WEEK.
  • 26 weeks (Gavage)  (C97011F)  Completed 
    • Mice: FVB/N; Mice: Tg.AC (FVB/N) Homozygous
    • Dose: TG.AC MICE AT 0, 33, 265, OR 530 UG/KG AND FVB MICE AT 0 OR 530 UG/KG; 15/SEX/DOSE; 2X/WEEK.