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Testing Status of Goldenseal extract M980047

CASRN: 84603-60-1

Synonyms/Common Names

  • EGS
  • Extract of goldenseal
  • Goldenseal, Hydrastis canadensis extract
  • Hydrastis canadensis extract

Short-Term Toxicity

  • 5 days (Gavage)  (C98047)  Data in Review 
    • 5 day
    • Rats: F344/NCrl (SAS FISCH)
    • Dose: Golden Seal Extract; 0, 94, 188, 375, 750, or 1500 mg/kg; 6 males/group.

Genetic Toxicology

  • 5 days Micronucleus (Gavage)  (G98047)  Completed 
    • Rats: F344/N Charles River
  • 24 hours Micronucleus (in-vitro) Selected (G98047C)  
    • Human (Cell Lines)
  • Salmonella (in-vitro) Selected (G98047B)