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Testing Status of Acetoin M990018

 

CASRN: 513-86-0

Formula: C4-H8-O2

Synonyms/Common Names

  • Acetyl methyl carbinol
  • 3-Hydroxy-2-butanone

Short-Term Toxicity

  • 14 days (Inhalation)  (C20724)  Completed 
    • TOX-98 
      Toxicity Studies of Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN 600-14-6) Administered by Inhalation to Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice
    • Rats: Wistar Han; Mice: B6C3F1
    • Dose: 0, 6.25, 25, 100, 400, or 800 ppm; 5/sex/species/conc.
  • 90 days (Inhalation)  (C20724)  Completed 
    • TOX-98 
      Toxicity Studies of Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN 600-14-6) Administered by Inhalation to Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice
    • Rats: Wistar Han; Mice: B6C3F1
    • Dose: R&M: 0, 50, 100, 200, 400, or 800 ppm -- R: 20/sex/conc; M: 10/sex/conc.

Genetic Toxicology

  • Micronucleus  (G99018)  Completed 
    • Rats: Wistar Han
    • Male Negative 
    • Female Negative 
  • Micronucleus  (G99018B)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (A17696)  Completed 
    •  Negative