National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n20003

Nomination Summary for Plumbagin (N20003)

Plumbagin

Specific Substances: Plumbagin

Nomination Date: 10/25/1999

Nominator: NCI

Rationale: Plumbagin is a natural yellow pigment that may have toxic properties. Human exposure occurs primarily through its use in folk medicines & recently marketed dietary supplements. There is much evidence to suggest that plumbagin may have potential as a chemotherapeutic or chemopreventive agent. Plumbagin has been identified as a redox-cycling agent that also induces DNA cleavage and demonstrates reproductive toxicity.

NTP Principles: not specified

Status: No Testing


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

Back to Top

CASRN: 481-42-5

Agent Name: Plumbagin

  • No studies are available.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.