National Toxicology Program

National Toxicology Program

Nomination Summary for Polybrominated diphenyl ethers (N20010)

Polybrominated diphenyl ethers

Specific Substances: 2,2',4,4',5,5'-Hexabromodiphenyl ether (PBDE 153), Octabromodiphenyl ether, 2,2',4,4',5-Pentabromodiphenyl Ether, Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)], 2,2',4,4'-Tetrabromodiphenyl Ether

Nomination Date: 12/08/1999

Nominator: California EPA

Rationale: High production volume flame retardants; widespread human exposure occupationally and as environmental contaminants; persistent and bioaccumulative; evidence for toxicity but significant knowledge gaps remain

NTP Principles: 1, 2, 5

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 68631-49-2

Agent Name: 2,2',4,4',5,5'-Hexabromodiphenyl ether (PBDE 153)

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CASRN: 32536-52-0

Agent Name: Octabromodiphenyl ether

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CASRN: 60348-60-9

Agent Name: 2,2',4,4',5-Pentabromodiphenyl Ether

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CASRN: 32534-81-9

Agent Name: Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)]

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CASRN: 5436-43-1

Agent Name: 2,2',4,4'-Tetrabromodiphenyl Ether

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.