Nomination Date: 02/04/2000
Nominator: NIEHS, EPA
Rationale: Aluminum is a listed by the EPA as a drinking water contaminant with a high health research priority. Since aluminum is found in nearly all drinking water and fluoridation may enhance absorption, there is a need for long-term low concentration rodent studies. The effects of aluminum citrate & aluminum fluoride complexes on body burdens of aluminum including the brain need to be evaluated.