National Toxicology Program

National Toxicology Program

Nomination Summary for Accutane (N20027)


Specific Substances: 13-cis-Retinoic acid

Nomination Date: 03/30/2000

Nominator: Private Individual

Rationale: Accutane is prescribed for the treatment of acne, but it can induce serious adverse effects in young adults. Examples of adverse effects include severe depression and suicide, seizures, liver toxicity, immune dysfunction , central nervous system damage, etc.

NTP Principles: not specified

Status: In Review/Pending

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 4759-48-2

Agent Name: 13-cis-Retinoic acid

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.