National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n20031

Nomination Summary for Microcystin LR (N20031)

Microcystin LR

Specific Substances: Microcystin LR

Nomination Date: 05/18/2000

Nominator: NIEHS

Rationale: Cyanobacteria, a blue-green algae associated with eutrophication, and their toxins have been identified by the EPA as drinking water contaminants with high health research priority. Research shows that microcystins, the most common toxins associated with blue-green algae blooms, are hepatotoxic. Incidences of gastroenteritis affecting 1000's of people have been associated with algae blooms. However, very little is known about the chronic low dose effects of microcystin exposure associated with drinking water.

NTP Principles: 1, 2

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 101043-37-2

Agent Name: Microcystin LR

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.