Specific Substances: Black Cohosh
Nomination Date: 05/31/2000
Nominator: NCI, NIEHS
Rationale: Black cohosh is a dietary supplement used for the treatment of menstrual and menopausal symptoms in women. Black cohosh appears to bind to estrogen receptors and causes luteinizing hormone suppression. No chronic studies in humans or animals demonstrating the safety of black cohosh were found.