Nomination Summary for Lemon oil & Lime oil (N20101)
Nomination Date: 10/10/2000
Rationale: Lemon and lime oils are added as fragrances to cosmetic products including some products intended for use on sun-exposed skin. Studies have shown that lemon and lime oil are phototoxic. Safe use levels have been recommended for avoiding short-term phototoxicity, but long-term use and effects have not been addressed. The phototoxicity elicited by lemon and lime oils has been associated with naturally occurring furocoumarins. While the photogenotoxicity of 5- methoxypsoralen is well established, the photogenotoxicity of oxypeucedanin alone or in mixtures has not been assessed.
Agents and Status
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.
Agent Name: Lemon oil
Agent Name: Lime oil
Agent Name: 5-Methoxypsoralen