National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n20218

Nomination Summary for Ketamine hydrochloride (N20218)

Ketamine hydrochloride

Specific Substances: Ketamine hydrochloride

Nomination Date: 03/26/2002

Nominator: FDA

Rationale: Approved drug for anesthetic use in adults; off-label pediatric use thought to occur; causes severe lesions in developing rat brain; further studies needed to assess safety of pediatric use

NTP Principles: 2, 3

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 1867-66-9

Agent Name: Ketamine hydrochloride

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.