Nomination Summary for Gum guggul and Some of its Steroidal Constituents (N20333)

Nominated Substances: Guggulsterone, E-guggulsterone, Z-Guggulsterone, Gum Guggul Extract

Nomination Date: 04/15/2003

Nominator: NIEHS

Rationale: Consumer exposure through increasing dietary supplement use; demonstrated metabolic and hormonal effects; lack of adequate toxicological data

NTP Principles: 5, 6

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 95975-55-6

Agent Name: Guggulsterone

  • No studies are available.

CASRN: 39025-24-6

Agent Name: E-guggulsterone

  • No studies are available.

CASRN: 39025-23-5

Agent Name: Z-Guggulsterone

  • No studies are available.

CASRN: GUMGUGGULEXT

Agent Name: Gum Guggul Extract