National Toxicology Program

National Toxicology Program

Nomination Summary for 2-Methoxy-4-nitroaniline (N20613)


Specific Substances: 2-Methoxy-4-nitroaniline

Nomination Date: 04/26/2006

Nominator: NCI

Rationale: It is used in dyeing textiles, as a dye in the printing industry, and as an intermediate in the synthesis of Azo dyes in tattoo inks, emulsion paints and toy enamels. Given the concerns about other anisidines, findings that this agent is mutagenic when metabolically activated raises concerns about the carcinogenic potential of this compound.

NTP Principles: 1, 6, 7

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 97-52-9

Agent Name: 2-Methoxy-4-nitroaniline

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.