National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n20812

Nomination Summary for Dong quai (Angelica sinensis root [308068-61-3] and extract [299184-76-2]) (N20812)

Dong quai (Angelica sinensis root [308068-61-3] and extract [299184-76-2])

Specific Substances: 3-Butylidenephthalide [551-08-6], Dong quai Angelica sinensis root, Dong quai Angelica sinensis root extract, Ferulic Acid [1135-24-6], Ligustilide [4431-01-0]

Nomination Date: 08/20/2008

Nominator: Private Individual

Rationale: Widespread use as a dietary supplement; suspicion of toxicity based on estrogenic activity and chemical structure; lack of adequate toxicity data

NTP Principles: not specified

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 551-08-6

Agent Name: 3-Butylidenephthalide [551-08-6]

  • No studies are available.

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CASRN: 308068-61-3

Agent Name: Dong quai Angelica sinensis root

  • No studies are available.

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CASRN: 299184-76-2

Agent Name: Dong quai Angelica sinensis root extract

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CASRN: 1135-24-6

Agent Name: Ferulic Acid [1135-24-6]

  • No studies are available.

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CASRN: 4431-01-0

Agent Name: Ligustilide [4431-01-0]

  • No studies are available.
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