National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n21010

Nomination Summary for Ionic Liquids Class Study (N21010)

Ionic Liquids Class Study

Specific Substances: PEG-5 cocomonium methosulfate, Distearyldimethylammonium chloride, 1-Methylimidazolium chloride

Nomination Date: 06/07/2006

Nominator: NCI

Rationale: Ionic liquids are intended as replacements for volatile organic chemicals (VOCs) and significant human exposure to ionic liquids might occur if safety precautions are not followed when they are used in industrial processes. Of all the possible combinations of anions and cations, only the ionic liquid 1-methylimidazolium chloride is in full-scale commercial use. Due to its structural similarity to the already nominated compound 1-butyl-3-methylimidazolium chloride, NCI requests testing of 1-methylimidazolium chloride focusing on potential differences in how these two compounds are retained in the body.

NTP Principles: not specified

Status: Received


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 68989-03-7

Agent Name: PEG-5 cocomonium methosulfate

  • No studies are available.

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CASRN: 107-64-2

Agent Name: Distearyldimethylammonium chloride

  • No studies are available.

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CASRN: 35487-17-3

Agent Name: 1-Methylimidazolium chloride

  • No studies are available.
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