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Nomination Summary for Trimethylsilyldiazomethane (TMSD) (N21110)

Nominated Substances: Trimethylsilyldiazomethane (TMSD)

Nomination Date: 07/05/2011

Nominator: OSHA

Rationale: Low volume production and use as a reagent in synthetic and analytical chemistry; developed and promoted as a safer substitute for diazomethane; inadequate toxicological data; case reports of severe lung injury and death in exposed laboratory personnel

NTP Principles: not specified


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 18107-18-1

Agent Name: Trimethylsilyldiazomethane (TMSD)