Nomination Date: 11/05/2012
Nominator: Private Individual
Rationale: Although some of these components have been studied individually, there is not sufficient or adequate toxicological information available to fully assess the short-term and long-term safety of these enhanced drinks which contain mixtures of multiple compounds. The nomination of a mixture of energy drink components is further based on the popularity of energy drinks (especially among young adults), potential high levels of exposure, and possibility of chronic exposure. A mixture of caffeine, taurine, and guarana in a formulation at ratios commonly used in commercially-available energy drinks should minimally be considered. Consideration should also be given to inclusion of ginseng, inositol, L-carnitine, and/or the B vitamins.
NTP Principles: not specified
Status: In Review
Agents and Status
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.
Agent Name: Acetyl-l-carnitine hydrochloride
Agent Name: Caffeine
Agent Name: Ginkgo biloba extract
Agent Name: Ginseng
Agent Name: Guarana
Agent Name: Inositol
Agent Name: Milk thistle extract
Agent Name: L-Taurine