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Nomination Summary for Nanoscale Cellulose (N21304)

Nominated Substances: Microcrystalline cellulose

Nomination Date: 08/04/2010

Nominator: NIEHS

Rationale: Anticipated increase in production due to natural abundance and functional properties that make it useful for a wide range of industrial applications; suspicion of toxicity based on known hazard of other respirable crystalline particles, high aspect ratio and large surface area of nanoscale form; very limited toxicological data available for nanoscale cellulose particularly via inhalation, the exposure route of greatest concern in industrial settings.

NTP Principles: not specified

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