Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Nomination Summary for Estragole (N79475)

Nominated Substances: Estragole

Nomination Date: 09/00/1979

Nominator: NCI

Rationale: Nominated due to its structural similarity to the known carcinogen, safrole, and preliminary carcinogenicity studies in which it induced significant incidences of hepatocellular carcinomas in preweanling mice following subcutaneous injections. Estragole has the potential for wide-spread human exposure since it is used as a food flavoring agent and as a fragrance.

NTP Principles: Pre 1993 - 1, 3, 5


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 140-67-0

Agent Name: Estragole