Nomination Summary for Tripelennamine (N80303)

Nominated Substances: Doxylamine, Promethazine, Pyrilamine, Tripelennamine

Nomination Date: 10/00/1979

Nominator: FDA

Rationale: Concern as to potential increased usage as substitute for methapyrilene, which was shown to be carcinogenic - lack of adequate toxicity data

NTP Principles: Pre 1993 - 2, 6


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 469-21-6

Agent Name: Doxylamine


CASRN: 60-87-7

Agent Name: Promethazine

  • No studies are available.

CASRN: 91-84-9

Agent Name: Pyrilamine


CASRN: 91-81-6

Agent Name: Tripelennamine

  • No studies are available.