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Nomination Summary for Chemicals with TLVs (N81102)

Nominated Substances: Allyl propyl disulfide, 2-Aminopyridine, tert-Butyl chromate, o-sec-Butylphenol, tert-Butyltoluene, o-Chlorobenzalmalononitrile (CS), Chlorostyrene, 2-Chloro-6-(trichloromethyl)pyridine, 2-(Dibutylamino)ethanol, 1,1-Dichloro-1-nitroethane, Divinylbenzene, Ethylidenenorbornene, N-Ethylmorpholine, Formamide, Hexachloronaphthalene, Isophorone diisocyanate, N-Isopropylaniline, Methacrylonitrile, Methyl 2-cyanoacrylate, Methyl demeton, Methylenebis(4-cyclohexyl isocyanate), N-Methyl-2-pyrrolidone, Octachloronaphthalene, Phenothiazine, Phenylphosphine, Piperazine dihydrochloride, 2-Pivalyl-1,3-indandione, Tetrachloronaphthalene, Tetraethyldithiopyrophosphate, Tetramethylsuccinonitrile, Triphenylamine

Nomination Date: 08/00/1981

Nominator: NIOSH

Rationale: Assess mutagenic activity of group of chemicals with tlvs to determine which chemicals should be tested in chronic studies.

NTP Principles: Pre 1993 - 3

Status: In Review/Pending


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 2179-59-1

Agent Name: Allyl propyl disulfide


CASRN: 504-29-0

Agent Name: 2-Aminopyridine


CASRN: 1189-85-1

Agent Name: tert-Butyl chromate

  • No studies are available.

CASRN: 89-72-5

Agent Name: o-sec-Butylphenol


CASRN: 27138-21-2

Agent Name: tert-Butyltoluene

  • No studies are available.

CASRN: 2698-41-1

Agent Name: o-Chlorobenzalmalononitrile (CS)


CASRN: 1331-28-8

Agent Name: Chlorostyrene

  • No studies are available.

CASRN: 1929-82-4

Agent Name: 2-Chloro-6-(trichloromethyl)pyridine


CASRN: 102-81-8

Agent Name: 2-(Dibutylamino)ethanol


CASRN: 594-72-9

Agent Name: 1,1-Dichloro-1-nitroethane


CASRN: 1321-74-0

Agent Name: Divinylbenzene


CASRN: 16219-75-3

Agent Name: Ethylidenenorbornene


CASRN: 100-74-3

Agent Name: N-Ethylmorpholine


CASRN: 75-12-7

Agent Name: Formamide


CASRN: 1335-87-1

Agent Name: Hexachloronaphthalene

  • No studies are available.

CASRN: 4098-71-9

Agent Name: Isophorone diisocyanate


CASRN: 768-52-5

Agent Name: N-Isopropylaniline


CASRN: 126-98-7

Agent Name: Methacrylonitrile


CASRN: 137-05-3

Agent Name: Methyl 2-cyanoacrylate


CASRN: 8022-00-2

Agent Name: Methyl demeton

  • No studies are available.

CASRN: 5124-30-1

Agent Name: Methylenebis(4-cyclohexyl isocyanate)

  • No studies are available.

CASRN: 872-50-4

Agent Name: N-Methyl-2-pyrrolidone


CASRN: 2234-13-1

Agent Name: Octachloronaphthalene


CASRN: 92-84-2

Agent Name: Phenothiazine


CASRN: 638-21-1

Agent Name: Phenylphosphine

  • No studies are available.

CASRN: 142-64-3

Agent Name: Piperazine dihydrochloride

  • No studies are available.

CASRN: 83-26-1

Agent Name: 2-Pivalyl-1,3-indandione


CASRN: 1335-88-2

Agent Name: Tetrachloronaphthalene

  • No studies are available.

CASRN: 3689-24-5

Agent Name: Tetraethyldithiopyrophosphate


CASRN: 3333-52-6

Agent Name: Tetramethylsuccinonitrile


CASRN: 603-34-9

Agent Name: Triphenylamine