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Nomination Summary for Genotoxic potential of flavoring agents (N81302)

Nominated Substances: Allyl anthranilate, Anethole, Butyl anthranilate, Cadinene, Carveol, Carvyl acetate, Cinnamaldehyde ethylene glycol acetal, Citral, Citral diethyl acetal, Cyclohexyl anthranilate, Ethyl anthranilate, Ethyl-3-methyl-3-phenylglycidate, Ethyl 3-phenylglycidate, Ethylvanillin, Furfural acetone, Furfuryl acetate, beta-2-Furylacrolein, beta-Ionone, Isobutyl anthranilate, Isoeugenol, Linalyl anthranilate, Maltol, o-Methoxycinnamaldehyde, Methyl anthranilate, alpha-Methyl cinnamaldehyde, Musk ambrette, Musk ketone, Phenethyl anthranilate, Piperonal acetone, Piperonyl acetate, 3-Propylidenephthalide, Vanillin, Veratraldehyde

Nomination Date: 01/00/1981

Nominator: NIEHS

Rationale: Using Salmonella, assess the genotoxic potential of flavoring agents.

NTP Principles: Pre 1993 - 3


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 7493-63-2

Agent Name: Allyl anthranilate


CASRN: 104-46-1

Agent Name: Anethole


CASRN: 7756-96-9

Agent Name: Butyl anthranilate


CASRN: 29350-73-0

Agent Name: Cadinene


CASRN: 99-48-9

Agent Name: Carveol


CASRN: 97-42-7

Agent Name: Carvyl acetate


CASRN: 5392-40-5

Agent Name: Citral


CASRN: 7492-66-2

Agent Name: Citral diethyl acetal


CASRN: 7779-16-0

Agent Name: Cyclohexyl anthranilate


CASRN: 87-25-2

Agent Name: Ethyl anthranilate


CASRN: 77-83-8

Agent Name: Ethyl-3-methyl-3-phenylglycidate


CASRN: 121-39-1

Agent Name: Ethyl 3-phenylglycidate


CASRN: 121-32-4

Agent Name: Ethylvanillin


CASRN: 623-15-4

Agent Name: Furfural acetone


CASRN: 623-17-6

Agent Name: Furfuryl acetate


CASRN: 623-30-3

Agent Name: beta-2-Furylacrolein


CASRN: 14901-07-6

Agent Name: beta-Ionone


CASRN: 7779-77-3

Agent Name: Isobutyl anthranilate


CASRN: 97-54-1

Agent Name: Isoeugenol


CASRN: 7149-26-0

Agent Name: Linalyl anthranilate


CASRN: 118-71-8

Agent Name: Maltol


CASRN: 1504-74-1

Agent Name: o-Methoxycinnamaldehyde


CASRN: 134-20-3

Agent Name: Methyl anthranilate


CASRN: 101-39-3

Agent Name: alpha-Methyl cinnamaldehyde


CASRN: 83-66-9

Agent Name: Musk ambrette


CASRN: 81-14-1

Agent Name: Musk ketone


CASRN: 133-18-6

Agent Name: Phenethyl anthranilate


CASRN: 3160-37-0

Agent Name: Piperonal acetone


CASRN: 326-61-4

Agent Name: Piperonyl acetate


CASRN: 17369-59-4

Agent Name: 3-Propylidenephthalide


CASRN: 121-33-5

Agent Name: Vanillin


CASRN: 120-14-9

Agent Name: Veratraldehyde