National Toxicology Program

National Toxicology Program

Nomination Summary for Fumaric acid (N81304)

Fumaric acid

Nominated Substances: Fumaric acid

Nomination Date: 10/00/1980

Nominator: NCI, CPSC

Rationale: High exposure based on use in puddings and gelatin mixes. Role as an intermediate in the tricarboxylic acid cycle and potential for accumulation of metabolic products after its administration to animals in large doses.

NTP Principles: Pre 1993 - 3

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 110-17-8

Agent Name: Fumaric acid

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.