Nomination Summary for Salmonella assay for group of nitriles (N82323)

Nominated Substances: Acrylonitrile, Adiponitrile, Benzonitrile, Cyclohexanone cyanohydrin, Diaminomaleonitrile, Hydroxyacetonitrile, alpha-Hydroxybenzeneacetonitrile, 2-Hydroxy-2-methylpropanenitrile, 2-Hydroxypropanenitrile, 3-Hydroxypropanenitrile, Malonic dinitrile, 2-Methyl-3-butenenitrile, cis-2-Methyl-2-butenenitrile, trans-2-Methyl-2-butenenitrile, Methylglutaronitrile, cis-2-Pentenenitrile, trans-2-Pentenenitrile, 3-Pentenenitrile, Phenylacetonitrile, Propylene cyanohydrin, Succinonitrile, o-Tolunitrile, p-Tolunitrile, Valeronitrile

Nomination Date: 03/00/1982

Nominator: NIEHS

Rationale: Assess genotoxic potential of group of nitriles in Salmonella assay

NTP Principles: Pre 1993 - 3


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 107-13-1

Agent Name: Acrylonitrile


CASRN: 111-69-3

Agent Name: Adiponitrile


CASRN: 100-47-0

Agent Name: Benzonitrile


CASRN: 931-97-5

Agent Name: Cyclohexanone cyanohydrin


CASRN: 1187-42-4

Agent Name: Diaminomaleonitrile


CASRN: 107-16-4

Agent Name: Hydroxyacetonitrile


CASRN: 532-28-5

Agent Name: alpha-Hydroxybenzeneacetonitrile


CASRN: 75-86-5

Agent Name: 2-Hydroxy-2-methylpropanenitrile


CASRN: 78-97-7

Agent Name: 2-Hydroxypropanenitrile


CASRN: 109-78-4

Agent Name: 3-Hydroxypropanenitrile


CASRN: 109-77-3

Agent Name: Malonic dinitrile


CASRN: 16529-56-9

Agent Name: 2-Methyl-3-butenenitrile


CASRN: 20068-02-4

Agent Name: cis-2-Methyl-2-butenenitrile

  • No studies are available.

CASRN: 30574-97-1

Agent Name: trans-2-Methyl-2-butenenitrile

  • No studies are available.

CASRN: 4553-62-2

Agent Name: Methylglutaronitrile


CASRN: 25899-50-7

Agent Name: cis-2-Pentenenitrile

  • No studies are available.

CASRN: 26294-98-4

Agent Name: trans-2-Pentenenitrile

  • No studies are available.

CASRN: 4635-87-4

Agent Name: 3-Pentenenitrile


CASRN: 140-29-4

Agent Name: Phenylacetonitrile


CASRN: 2567-01-3

Agent Name: Propylene cyanohydrin

  • No studies are available.

CASRN: 110-61-2

Agent Name: Succinonitrile


CASRN: 529-19-1

Agent Name: o-Tolunitrile


CASRN: 104-85-8

Agent Name: p-Tolunitrile


CASRN: 110-59-8

Agent Name: Valeronitrile