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Nomination Summary for Salmonella assay for group of nitriles (N82323)

Nominated Substances: Acrylonitrile, Adiponitrile, Benzonitrile, Cyclohexanone cyanohydrin, Diaminomaleonitrile, Hydroxyacetonitrile, alpha-Hydroxybenzeneacetonitrile, 2-Hydroxy-2-methylpropanenitrile, 2-Hydroxypropanenitrile, 3-Hydroxypropanenitrile, Malonic dinitrile, 2-Methyl-3-butenenitrile, cis-2-Methyl-2-butenenitrile, trans-2-Methyl-2-butenenitrile, Methylglutaronitrile, cis-2-Pentenenitrile, trans-2-Pentenenitrile, 3-Pentenenitrile, Phenylacetonitrile, Propylene cyanohydrin, Succinonitrile, o-Tolunitrile, p-Tolunitrile, Valeronitrile

Nomination Date: 03/00/1982

Nominator: NIEHS

Rationale: Assess genotoxic potential of group of nitriles in Salmonella assay

NTP Principles: Pre 1993 - 3

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 107-13-1

Agent Name: Acrylonitrile

CASRN: 111-69-3

Agent Name: Adiponitrile

CASRN: 100-47-0

Agent Name: Benzonitrile

CASRN: 931-97-5

Agent Name: Cyclohexanone cyanohydrin

CASRN: 1187-42-4

Agent Name: Diaminomaleonitrile

CASRN: 107-16-4

Agent Name: Hydroxyacetonitrile

CASRN: 532-28-5

Agent Name: alpha-Hydroxybenzeneacetonitrile

CASRN: 75-86-5

Agent Name: 2-Hydroxy-2-methylpropanenitrile

CASRN: 78-97-7

Agent Name: 2-Hydroxypropanenitrile

CASRN: 109-78-4

Agent Name: 3-Hydroxypropanenitrile

CASRN: 109-77-3

Agent Name: Malonic dinitrile

CASRN: 16529-56-9

Agent Name: 2-Methyl-3-butenenitrile

CASRN: 4553-62-2

Agent Name: Methylglutaronitrile

CASRN: 4635-87-4

Agent Name: 3-Pentenenitrile

CASRN: 140-29-4

Agent Name: Phenylacetonitrile

CASRN: 110-61-2

Agent Name: Succinonitrile

CASRN: 529-19-1

Agent Name: o-Tolunitrile

CASRN: 104-85-8

Agent Name: p-Tolunitrile

CASRN: 110-59-8

Agent Name: Valeronitrile