National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n85204

Nomination Summary for Dimethylformamide (N85204)

Dimethylformamide

Specific Substances: Dimethylformamide

Nomination Date: 06/05/1984

Nominator: NIOSH

Rationale: Dimethylformamide (DMF) is widely used as a solvent and most commonly used in the manufacture of polymers, protective coatings, adhesives, films and printing inks. This wide application, coupled with its volatility and its ability to readily penetrate intact skin, denotes that DMF may pose significant health hazards to man during its manufacture, distribution, and use. The experimental data is inadequate. Reports from teratological studies report no fetal malformations but can produce increased fetal deaths when the doses approach the lethal level for the female parent of the species.

NTP Principles: not specified

Status: No Testing


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 68-12-2

Agent Name: Dimethylformamide

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.