National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n92001

Nomination Summary for Tamoxifen (N92001)

Tamoxifen

Specific Substances: Tamoxifen citrate

Nomination Date: 05/15/1992

Nominator: Private Individual

Rationale: Scientific evidence of unacceptable risk in the absence of disease; evidence that Tamoxifen may induce or promote the development of aggressive hormone independent tumors, increase the risk of life-threatening liver cancer; increase the risk of endometrial cancer; increase the risk of developing contralateral breast cancer in premenopausal women; act as a teratogen on the developing human genital tract.

NTP Principles: not specified

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 54965-24-1

Agent Name: Tamoxifen citrate

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.