Specific Substances: Tamoxifen citrate
Nomination Date: 05/15/1992
Nominator: Private Individual
Rationale: Scientific evidence of unacceptable risk in the absence of disease; evidence that Tamoxifen may induce or promote the development of aggressive hormone independent tumors, increase the risk of life-threatening liver cancer; increase the risk of endometrial cancer; increase the risk of developing contralateral breast cancer in premenopausal women; act as a teratogen on the developing human genital tract.
NTP Principles: not specified