National Toxicology Program

National Toxicology Program

Nomination Summary for Dicyclohexylcarbodiimide (DCC) / Diisopropylcarbodiimide (DIC) (N93101)

Dicyclohexylcarbodiimide (DCC) / Diisopropylcarbodiimide (DIC)

Specific Substances: Dicyclohexylcarbodiimide, Diisopropylcarbodiimide

Nomination Date: 06/15/1993

Nominator: NCI

Rationale: Human exposure; lack of adequate data. These compounds show acute toxicity and are potent sensitizers, have produced severe contact dermatitis, severe eye irritation, and delayed-onset temporary blindness.

NTP Principles: 3, 6, 7

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 538-75-0

Agent Name: Dicyclohexylcarbodiimide

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CASRN: 693-13-0

Agent Name: Diisopropylcarbodiimide

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.