National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n95026

Nomination Summary for Dimethylaminopropyl chloride, hydrochloride (N95026)

Dimethylaminopropyl chloride, hydrochloride

Specific Substances: Dimethylaminopropyl chloride, hydrochloride

Nomination Date: 07/05/1995

Nominator: NCI

Rationale: Dimethylaminopropyl chloride, hydrochloride (DMPC) has the potential for human exposure because of its wide use as an industrial and research organic intermediate. It is a member of the nitrogen mustard-type chemical class, which is associated with genetic toxicity and DNA damaging effects. DMPC was mutagenic in Salmonella strains with and without metabolic activation.

NTP Principles: 1, 7

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 5407-04-5

Agent Name: Dimethylaminopropyl chloride, hydrochloride

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.