Nominated Substances: Dimethylaminopropyl chloride, hydrochloride
Nomination Date: 07/05/1995
Rationale: Dimethylaminopropyl chloride, hydrochloride (DMPC) has the potential for human exposure because of its wide use as an industrial and research organic intermediate. It is a member of the nitrogen mustard-type chemical class, which is associated with genetic toxicity and DNA damaging effects. DMPC was mutagenic in Salmonella strains with and without metabolic activation.