Specific Substances: Melatonin
Nomination Date: 09/04/1995
Rationale: Melatonin, a hormone produced by the pineal gland, has become very popular as an over-the-counter hormone supplement as well as being used as a chemotherapeutic agent in cancer. A literature search reveals a lack of toxicity studies. In addition, it has been suggested that melatonin may have the potential to cause ocular toxicity.