National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n97001

Nomination Summary for Tryptophan microcontaminants (N97001)

Tryptophan microcontaminants

Specific Substances: 1,1-Ethylidenebis(tryptophan), 3-(Phenylamino)alanine

Nomination Date: 11/02/1996

Nominator: Private Individual

Rationale: Some people who used the dietary supplement L-tryptophan developed illnesses such as eosinophilia-myalgia syndrome (EMS). It was hypothesized that tryptophan microcontaminants such as 1, 1-ethylidenebis(tryptophan) (EBT) and 3-phenylamino) alanine (PAA) were responsible for the reported illnesses.

NTP Principles: not specified

Status: In Review/Pending


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 132685-02-0

Agent Name: 1,1-Ethylidenebis(tryptophan)

  • No studies are available.

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CASRN: 145545-23-9

Agent Name: 3-(Phenylamino)alanine

  • No studies are available.
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