Specific Substances: Myristicin
Nomination Date: 09/30/1997
Rationale: Myristicin's nomination is based on its potential for widespread human exposure through foods and beverages and the possibility of adverse effects in diverse populations. Myristicin is the hallucinogenic agent in nutmeg and mace. Myristicin may have the potential to be both a carcinogen and an anti-carcinogen. It may have the ability to inhibit liver tumor formation in mice exposed to carbon tetrachloride. However, myristicin is closely related to safrole, a liver carcinogen in mice and rats.