National Toxicology Program

National Toxicology Program

Nomination Summary for Myristicin (N97032)


Nominated Substances: Myristicin

Nomination Date: 09/30/1997

Nominator: NCI

Rationale: Myristicin's nomination is based on its potential for widespread human exposure through foods and beverages and the possibility of adverse effects in diverse populations. Myristicin is the hallucinogenic agent in nutmeg and mace. Myristicin may have the potential to be both a carcinogen and an anti-carcinogen. It may have the ability to inhibit liver tumor formation in mice exposed to carbon tetrachloride. However, myristicin is closely related to safrole, a liver carcinogen in mice and rats.

NTP Principles: 1, 2, 6, 7

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 607-91-0

Agent Name: Myristicin

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.