Nomination Summary for Methylal (N97036)
Nominated Substances: Methylal
Nomination Date: 09/30/1997
Rationale: Methylal's nomination is based on: 1) its potential for occupational exposures based on high production volume (1.2-64 million lbs) and estimate of worker exposure; 2) evidence of occupational exposures based on TLV and other literature documentation; 3) potential for general population exposures based on use as a solvent in consumer products and occurrence in environmental media; 4) suspicion of carcinogenicity based on potential for metabolic release of formaldehyde and positive mutagenicity data; 5) lack of chronic toxicity data.
NTP Principles: 2