National Toxicology Program

National Toxicology Program

Nomination Summary for Methylal (N97036)


Specific Substances: Methylal

Nomination Date: 09/30/1997

Nominator: NCI

Rationale: Methylal's nomination is based on: 1) its potential for occupational exposures based on high production volume (1.2-64 million lbs) and estimate of worker exposure; 2) evidence of occupational exposures based on TLV and other literature documentation; 3) potential for general population exposures based on use as a solvent in consumer products and occurrence in environmental media; 4) suspicion of carcinogenicity based on potential for metabolic release of formaldehyde and positive mutagenicity data; 5) lack of chronic toxicity data.

NTP Principles: 2


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 109-87-5

Agent Name: Methylal

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.