National Toxicology Program

National Toxicology Program

Nomination Summary for Goldenseal & two of its constituent alkaloids (N98004)

Goldenseal & two of its constituent alkaloids

Specific Substances: Berberine, Berberine chloride dihydrate, Goldenseal extract, Goldenseal root powder, Hydrastine

Nomination Date: 11/00/1997

Nominator: NIEHS

Rationale: The nomination of goldenseal and two of its constituent alkaloids is based on the potential for human exposure and the lack of chronic or carcinogenicity data.

NTP Principles: 1, 2, 3, 5

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 2086-83-1

Agent Name: Berberine

  • No studies are available.

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CASRN: 5956-60-5

Agent Name: Berberine chloride dihydrate

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CASRN: 84603-60-1

Agent Name: Goldenseal extract

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Agent Name: Goldenseal root powder

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CASRN: 118-08-1

Agent Name: Hydrastine

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.