National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n98008

Nomination Summary for Bixin (N98008)

Bixin

Specific Substances: Annatto, Bixin

Nomination Date: 02/18/1998

Nominator: NCI

Rationale: The nomination of bixin is based on the high production volume and widespread exposure of the population to annatto, one of the most highly consumed colorants in the US food supply. Bixin is the ingredient that contributes this color. Despite annatto's status as an unregulated color additive, little is known about the toxicity of bixin or norbixin which are concentrated in annatto extracts and oils. A few short-term tests for genotoxicity of annatto have been described as positive.

NTP Principles: 1, 2

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

Back to Top

CASRN: 1393-63-1

Agent Name: Annatto

Back to Top

CASRN: 6983-79-5

Agent Name: Bixin

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.