National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/nm-n98018

Nomination Summary for Bentonite (N98018)

Bentonite

Specific Substances: Bentonite

Nomination Date: 08/14/1998

Nominator: NIOSH

Rationale: Bentonite is nominated for chronic inhalation studies to determine its potential to cause fibrotic lung disease. Reports note a relatively high incidence of fibrotic lung disease in workers exposed to bentonite. This elevated incidence rate has been ascribed to silica, which is present in varying degrees in bentonite. However, there is some evidence that bentonite itself can cause pneumoconiosis. Bentonite has a high potential for occupational exposure, and is currently not regulated in the workplace.

NTP Principles: 1, 2, 5

Status: Selected


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 1302-78-9

Agent Name: Bentonite

  • No studies are available.
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