National Toxicology Program

National Toxicology Program

Nomination Summary for Milk thistle extract (N99013)

Milk thistle extract

Specific Substances: Milk thistle extract, Silybin, Silymarin

Nomination Date: 04/14/1999

Nominator: NCI

Rationale: Use as a dietary supplement thought to have beneficial effects on the liver; limited safety information

NTP Principles: 2, 3

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 84604-20-6

Agent Name: Milk thistle extract

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CASRN: 22888-70-6

Agent Name: Silybin

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CASRN: 65666-07-1

Agent Name: Silymarin

NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.