National Toxicology Program

National Toxicology Program

Nomination Summary for DNA-based products (N99020)

DNA-based products

Specific Substances: Adenoviral vector (hGH), Adenoviral Vector (AdhAQP1), DNA-based products

Nomination Date: 05/19/1999

Nominator: FDA

Rationale: To assess safety concerns of DNA-based products such as 1) persistence and integration into the host's genome, 2) distribution to gonadal tissue, and 3) ectopic protein production and abnormal immune activation.

NTP Principles: 2, 4, 6

Status: Selected

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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Agent Name: Adenoviral vector (hGH)

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Agent Name: Adenoviral Vector (AdhAQP1)

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Agent Name: DNA-based products

  • No studies are available.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.