Testing Status of Ethylene glycol 2-ethylhexyl ether 08033

 

CASRN: 1559-35-9

Formula: C10-H22-O2

Synonyms/Common Names

  • EGEHE
  • Ethanol, 2-((2-ethylhexyl)oxy)-

Known Uses

The application of EGEHE for use in various formulations also appears to have increased (e.g., ink-jet inks, gas supply pipe sealant, electrodeposition coatings for catalytic converters, lens manufacturing cleaning solutions, termite repellent, liquid bleach and dishwashing detergents, flower preservatives, and air fresheners).

Chemical Properties

Toxicity Effects (HSDB)

Modified One-Generation

  • GD 6 to PND 28 Dose Range Finding (Gavage)  (MOG08033)  On Test 
    • Dose Range Finding
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 312.5, 625, 1250, or 2500 mg/kg/day.
  • F0 Generation (Gavage) Selected (MOG08033B)  
    • Rats: Harlan Sprague-Dawley
  • Fertility Assessment (Gavage) Selected (MOG08033B)  
    • Rats: Harlan Sprague-Dawley
  • Maternal Transfer (Gavage) Selected (MOG08033B)  
    • Rats: Harlan Sprague-Dawley
  • Neurotoxicology Assessment (Gavage) Selected (MOG08033B)  
    • Rats: Harlan Sprague-Dawley
  • 90 days Subchronic (Gavage) Selected (MOG08033B)  
    • Rats: Harlan Sprague-Dawley

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (K08033)  Completed 
    • Citation: Absorption, Distribution, Metabolism, and Excretion Studies of Ethylene Glycol 2-ethylhexyl ether (CAS# 1559-35-9) in Harlan Sprague Dawley Rats and B6C3F1/N Mice Following Gavage Administration, Intravenous Administration, or Dermal Application
    • Male and Female Rats: Harlan Sprague-Dawley; Male and Female Mice: B6C3F1/N
    • Dose: 150 mg/kg. 50, 150 or 500 mg/kg.

Organ Systems Toxicity

  • Immunotoxicity Selected (I08033)  
    • Developmental Immunotoxicity