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Testing Status of Serotype 5 Adeno-associated Viral Vector (rAAV5SCTLA4:Ig) 08043



Known Uses

Vector to be used to explore gene therapy in the treatment of rheumatoid arthritis and other autoimmune disorders.

Short-Term Toxicity

  • 13 weeks (Intraductal Cannulation)  (C08043)  Completed 
    • Mice: BALB/c
    • Dose: Core Group M&F: 0, 2x10e7, 2x10e8, 2x10e9, or 2x10e10 particles 21/group; Special M&F: 0, 2x10e10 particles 10/group.