National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-09029

Testing Status of Glucosamine Hydrochloride + Chondroitin Sulfate - 09029

 

CASRN: GLUCOSCHONDN

Formula: N/A

Secondary:

  • 9007-28-7 - Chondroitin sulfate
  • 66-84-2 - Glucosamine hydrochloride

Known Uses

Dietary supplements often used with in combination to alleviates pain and inflammation from osteoarthritis and reportedly has a beneficial effect on degenerated joints

Nomination Background

Short-Term Toxicity

  • 13 weeks (Gavage)  (C09029)  Completed 
    • Rats: Zucker - Lean (HsdHlr:ZUCKER-Lepr+); Rats: Zucker - Obese (HsdHlr:ZUCKER-Leprfa)
    • Dose: Male rats: 0/0; 30/24; 120/96; 300/240; or 600/480 mg/kg/bw/day; combination of glucosamine HCl/chondroitin sulfate; 12/dose lean and obese.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.