Testing Status of Nanoscale Material (Fullerene C60 18 microns) 09033
- Fullerene-C60 18 microns (Nanoscale material)
Part of an NTP evaluation of nanoscale materials (a broadly defined set of substances where at least one critical dimension is less than 100 nm) to evaluate the tox properties of major nanoscale materials classes representing a cross-section of composition, size, surface coatings, & physico-chemical properties, and use these as model systems to investigate how they interact w/ biological systems.
- 13 weeks (Gavage) Selected (C09033)
- Citation: Sayers BC, Germolec DR, Walker NJ, Shipkowski KA, Stout MD, Cesta MF, Roycroft JH, White KL, Jr., Baker GL, Dill JA, Smith MJ. Respiratory toxicity and immunotoxicity evaluations of microparticle and nanoparticle C60 fullerene aggregates in mice and rats following nose-only inhalation for 13 weeks. Nanotoxicology. 2016 Dec;10(10):1-39
- Rats: Wistar Han; Mice: B6C3F1