National Toxicology Program

National Toxicology Program

Testing Status of Valerian (Valeriana officinalis L.) root extract - 09042


CASRN: 8057-49-6

Related: Valerian (Valeriana officinalis L.) root oil [CASRN: 8008-88-6]

Formula: Unspecified

Synonyms/Common Names

  • Valerian extract, powdered

Known Uses

Dietary supplement used to treat a variety of ailments including insomnia, mood disorders, anxiety, menstrual cramps, and psychological stress conditions

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 90 days (Gavage)  (C09042)  On Test 
    • Mice: B6C3F1/N
    • Dose: 0, 125, 250, 500, 1000, or 2000 mg/kg.

Modified One-Generation

  • Dose Range Finding (Gavage)  (MOG09042)  On Test 
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 125, 250, 500, 1000, or 2000 mg/kg.

Genetic Toxicology

  • Micronucleus  (G09042)  On Test 
    • Male
    • Mice: B6C3F1
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.