Testing Status of Melamine cyanurate 10018

 

CASRN: 37640-57-6

Formula: C3-H6-N6.C3-H3-N3-O3

Synonyms/Common Names

  • 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, compd. with 1,3,5-triazine-2,4,6-triamine (1:1)

Known Uses

Flame retardant

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K10018)  Completed 
    • Citation: Jacob CC, Gamboa da Costa G. Low-level quantification of melamine and cyanuric acid in limited samples of rat serum by UPLC-electrospray tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Mar 15;879(9-10):652-6. doi: 10.1016/j.jchromb.2011.01.035. Epub 2011 Feb 21.Pubmed Abstract
    • Citation: Jacob CC, Reimschuessel R, Von Tungeln LS, Olson GR, Warbritton AR, Hattan DG, Beland FA, Gamboa da Costa G. Dose-response assessment of nephrotoxicity from a 7-day combined exposure to melamine and cyanuric acid in F344 rats. Toxicol Sci. 2011 Feb;119(2):391-7. doi: 10.1093/toxsci/kfq333. Epub 2010 Oct 28.Pubmed Abstract
    • Male and Female Rats: F344 (NCTR)
    • Dose: 1 mg/kg.