National Toxicology Program

National Toxicology Program

Testing Status of Epinephrine hydrochloride - 10041-V


CASRN: 55-31-2

Related: EPINEPHRINE (CAS 51-31-2)

Formula: C9-H13-N-O3.Cl-H

Synonyms/Common Names

  • (R)-4-(1-Hydroxy-2-(methylamino)ethyl)pyrocatechol hydrochloride

Known Uses

Adrenergic, vasoconstrictor, cardiac stimulant, bronchodilator

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Inhalation)  (C55663)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Inhalation)  (C55663)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 2.5, 40 MG/M3/10 PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C55663)  Report Complete 
    • TR-380 (NIH Number: 90-2835)  (Peer Review Approval 11/20/1989A )
      Toxicology and Carcinogenesis Studies of l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Inadequate Study 
      • Female Rats Inadequate Study 
      • Male Mice Inadequate Study 
      • Female Mice Inadequate Study 
    • Dose: R: 0, 1.5, 5.0, M: 0, 1.5, 3.0 MG/M3/50 PER GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.